Selected Articles

Dhooge W, Eertmans F and Comhaire F, Estrogen receptor based in vitro assays for the evaluation of endocrine disrupters. Folia Histochemica et Cytobiologica 39 Suppl 2 (2001) 38-39.
Dhooge W, Stuyvaert S, Kaufman JM, Koppen G, Nelen V, Schoeters G, van Larebeke N, Comhaire F, Observations as to male fertility in the Flemish Environment and Health Studies. Folia Histochemica et Cytobiologica 39 Suppl 2 (2001) 44-45.
Muthumbi W, De Boever P, D'Haese I, Dhooge W, Top EM, Pieters JG, Comhaire F and Verstraete W, Assessment of the estrogenic activity of flue gases from burning processes by means of the yeast based human estrogen receptor (hER) bioassay. Environ Technol (in press)
Tanghe T., Dhooge W., Verstraete W.; Formation of the metabolic intermediate 2,4,4-trimethyl-2-pentanol during incubation of a sphingomonas sp. strain with the xeno-estrogenic octylphenol. Biodegradation 11 (2000) 11-19.
Vandenbergh G., Janssen C., De Coen W., Dhooge W., Comhaire F.; Distribution and effects of environmental endocrine disrupters in Belgium. Water (2000).
Tanghe T., Dhooge W., Verstraete W. (1999) Isolation of a bacterial strain capable to degrade branched nonylphenol. Applied and Environmental Microbiology, 65(2), 746-751.
Tanghe T., Dhooge W., Verstraete W. (1999) Newly discovered Sphingomonad breaks down pseudoestrogens. Highlight in ASM News 65(4), 220.
Depuydt C.E., Mahmoud A.M., Dhooge W.S., Schoonjans F.A., Comhaire F.H.; Aspects of hormonal regulation of inhibin B secretion by immature rat Sertoli cells in vitro, and its possible use as a bioassay for estrogen detection. J. Andrology, 20(1) (1999) 54-62.
Van Waeleghem K., De Clercq N., Vermeulen L., Schoonjans F., Comhaire F. (1996) Deterioration of sperm quality in young healthy Belgian men. Hum.Reprod. 11, 325-329.

Literature from other research groups

Carlsen E., Giwercman A., Keiding N., Skakkebęk N.E. (1992) Evidence for decreasing quality of semen during past 50 years. Br.Med.J. 305, 609-613.
Colborn T., Vom Saal F.S., Soto A.M. (1993) Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ.Health Perspect. 101, 378-384.
Collins B.M., McLachlan J.A., Arnold S.F. (1997) The estrogenic and antiestrogenic activities of phytochemicals with the human estrogen expressed in yeast. Steroids 62, 365-372.
Cook J.C., Kaplan M., Davis L.G., O'Connor J.C. (1997) Development of a tier I screening battery for detecting endocrine-active compounds (EACs). Regul.Toxicol.Pharmacol. 26, 60-68.
Davis D.L., Bradlow H.L., Wolff M., Woodruff T., Hoel D.G., Anton-Culver H. (1993) Medical Hypothesis: xenoestrogens as preventable causes of breast cancer. Environ.Health Perspect. 101, 372-377.
Depuydt C.E., Mahmoud A.M., Dhooge W.S., Schoonjans F.A., Comhaire F.H. (1999) Aspects of hormonal regulation of inhibin B secretion by immature rat Sertoli cells in vitro, and its possible use as a bioassay for estrogen detection. J.Andrology 20, 54-62.
Desbrow C., Routledge E.J., Brighty G.C., Sumpter J.P., Waldock M. (1998) Identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening. Environ.Sci.Technol. 32(11), 1549-1558.
Fry D.M., Toone T.K. (1998) DDT-induced feminization of gull embryos. Science 213, 922-924.
Gimeno S., Gerritsen A., Bowmer T., Komen H. (1996) Feminization of male carp. Nature 384, 221-222.
Graumann K., Breithofer A., Jungbauer A. (1999) Monitoring of estrogen mimics by a recombinant yeast assay: synergy between natural and synthetic compounds? Sci.Total Environ. 225(1-2), 69-79
Harries J.E., Sheahan D.A., Jobling S., Matthiessen P., Neall P., Routledge E.J., Rycroft R., Sumpter J.P., Tylor T. (1996) A survey of estrogenic activity in United Kingdom inland waters. Environ.Toxicol.Chem. 15, 1993-2002.
Harris, C.A., Henttu, P., Parker, M.G., Sumpter, J.P. (1997) The estrogenic activity of phthalate esters in vitro. Environ.Health Perspect. 105, 802-811
Jensen T.K., Toppari J., Keiding N., Skakkebaek N.E. (1995) Do environmental estrogens contribute to the decline in male reproductive health? Clin.Chem. 41, 1896-1901.
Jobling S., Sheahan D., Osborne J.A., Matthiessen P., Sumpter J.P. (1996) Inhibition of testicular growth in rainbow trout (Oncorhynchus mykiss) exposed tot estrogenic alkylphenolic chemicals. Environ.Toxicol.Chem. 15, 194-202.
Routledge E.J., Sheahan D.A., Desbrow C., Brighty G.C., Waldock M., Sumpter J.P. 1998 Identification of estrogenic chemicals in STW effluent. 2. In vivo responses in trout and roach. Environ.Sci.Technol. 32, 1559-1565.
Schultz, T.W., Kraut, D.H., Sayler, G.S., Layton, A.C. (1998) Estrogenicity of selected biphenyls evaluated using recombinant yeast assay. Environ.Toxicol.Chem. 17(9), 1727-1729
Sohoni, P. & Sumpter, J.P. (1998). Several environmental oestrogens are also anti-androgens. J.Endocrinol. 158, 327-339.
Soto A.M., Sonnenschein C., Chung K.L., Fernandez M.F., Olea N., Serrano, F.O. (1995) The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants. Environ.Health Perspect. 103(Suppl 7), 113-122.
Tran D.Q., Ide C.F., McLachlan J.A., Arnold S.F. (1996) The anti-estrogenic activity of selected polynuclear aromatic hydrocarbons in yeast expressing human estrogen receptor. Biochem.Biophys.Res.Commun. 229, 102-108.

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